Investigational Drugs

Rilvegostomig

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Also known as:

AZD2936

Active trials that use this drug: 16

Cancer types include:

breast cancer cervical cancer colon cancer esophageal cancer gallbladder cancer +12 more

Sacituzumab tirumotecan

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Also known as:

sac-TMT MK-2870 SKB264

Active trials that use this drug: 15

Cancer types include:

breast cancer cervical cancer colon cancer esophageal cancer head and neck cancer +7 more

Datopotamab deruxtecan

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Also known as:

Dato-DXd DS-1062

Active trials that use this drug: 12

Cancer types include:

bladder cancer brain tumor breast cancer colon cancer non-small cell lung cancer +7 more

Avutometinib

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Also known as:

RG-7304 R-7304 CH-5126766 CKI-27 +2 more

Active trials that use this drug: 11

Cancer types include:

brain tumor breast cancer cervical cancer colon cancer head and neck cancer +7 more

BNT327

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Also known as:

Pumitamig PM8002 DB-1305

Active trials that use this drug: 11

Cancer types include:

breast cancer cervical cancer colon cancer head and neck cancer liver cancer +6 more

Zanzalintinib

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Also known as:

XL092

Active trials that use this drug: 11

Cancer types include:

cervical cancer head and neck cancer kidney cancer liver cancer pancreas cancer +3 more

Ifinatamab deruxtecan

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Also known as:

MK-2400 DS-7300 I-DXd

Active trials that use this drug: 10

Cancer types include:

breast cancer cervical cancer colon cancer esophageal cancer head and neck cancer +11 more

Volrustomig

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Also known as:

MEDI5752 PD-1/CTLA-4 DuetMab MEDI-5752

Active trials that use this drug: 9

Cancer types include:

cervical cancer colon cancer esophageal cancer head and neck cancer liver cancer +8 more

ZEN-3694

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Also known as:

ZEN003694

Active trials that use this drug: 9

Cancer types include:

breast cancer colon cancer ovarian cancer pancreas cancer prostate cancer +2 more

Defactinib

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Also known as:

PF-04554878 VS-6063

Active trials that use this drug: 8

Cancer types include:

brain tumor cervical cancer colon cancer head and neck cancer melanoma +4 more

Ivonescimab

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Also known as:

AK112/SMT112

Active trials that use this drug: 8

Cancer types include:

cervical cancer colon cancer head and neck cancer kidney cancer non-small cell lung cancer +4 more

LN-145

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Also known as:

lifileucel

Active trials that use this drug: 8

Cancer types include:

cervical cancer head and neck cancer melanoma non-small cell lung cancer sarcoma +3 more

Balstilimab

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Also known as:

BAL AGEN2034

Active trials that use this drug: 7

Cancer types include:

brain tumor cervical cancer colon cancer esophageal cancer head and neck cancer +5 more

Botensilimab

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Also known as:

BOT AGEN1181

Active trials that use this drug: 6

Cancer types include:

brain tumor cervical cancer colon cancer esophageal cancer head and neck cancer +4 more

JNJ-78278343

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Also known as:

pasritamig

Active trials that use this drug: 6

Cancer types include:

prostate cancer

RMC-6236

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Also known as:

A122

Active trials that use this drug: 6

Cancer types include:

colon cancer melanoma non-small cell lung cancer pancreas cancer rectal cancer +1 more

Ceralasertib

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Also known as:

AZD6738

Active trials that use this drug: 5

Cancer types include:

breast cancer cervical cancer colon cancer head and neck cancer kidney cancer +7 more

Debio 4228

No activity yet

Also known as:

degarelix

Active trials that use this drug: 5

Cancer types include:

prostate cancer

Giredestrant

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Also known as:

GDC-9545

Active trials that use this drug: 5

Cancer types include:

breast cancer uterine cancer

PDS0301

No activity yet

Also known as:

M-9241 NHS-IL12

Active trials that use this drug: 5

Cancer types include:

bladder cancer colon cancer kidney cancer liver cancer prostate cancer +2 more

Raludotatug Deruxtecan

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Also known as:

R-DXD DS-6000a

Active trials that use this drug: 5

Cancer types include:

non-small cell lung cancer ovarian cancer small cell lung cancer

Zimberelimab

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Also known as:

WBP-3055 GLS-010 AB122

Active trials that use this drug: 5

Cancer types include:

brain tumor breast cancer cervical cancer head and neck cancer kidney cancer +2 more

AZD5305

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Also known as:

saruparib

Active trials that use this drug: 4

Cancer types include:

breast cancer ovarian cancer prostate cancer small cell lung cancer uterine cancer

B7-H3 CAR-T

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Also known as:

B7-H3CART B7-H3-CAR T Cells TX103 4SCAR-276 +1 more

Active trials that use this drug: 4

Cancer types include:

kidney cancer melanoma ovarian cancer sarcoma

BMS-986504

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Also known as:

MRTX1719

Active trials that use this drug: 4

Cancer types include:

mesothelioma non-small cell lung cancer pancreas cancer sarcoma small cell lung cancer

Budigalimab

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Also known as:

PR-1648817 ABBV-181

Active trials that use this drug: 4

Cancer types include:

breast cancer cervical cancer colon cancer esophageal cancer head and neck cancer +6 more

fianlimab

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Also known as:

REGN3767

Active trials that use this drug: 4

Cancer types include:

melanoma ovarian cancer uterine cancer

HER3-DXd

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Active trials that use this drug: 4

Cancer types include:

bladder cancer breast cancer cervical cancer esophageal cancer head and neck cancer +8 more

Mervometostat

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Also known as:

EZH2i PF-06821497

Active trials that use this drug: 4

Cancer types include:

non-small cell lung cancer prostate cancer small cell lung cancer

MK-1084

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Active trials that use this drug: 4

Cancer types include:

colon cancer non-small cell lung cancer rectal cancer sarcoma small cell lung cancer

Opevesostat

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Also known as:

MK-5684

Active trials that use this drug: 4

Cancer types include:

prostate cancer

RMC-9805

Shows activity

Active trials that use this drug: 4

Cancer types include:

colon cancer non-small cell lung cancer pancreas cancer rectal cancer small cell lung cancer

SX-682

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Active trials that use this drug: 4

Cancer types include:

colon cancer non-small cell lung cancer pancreas cancer prostate cancer rectal cancer +1 more

Telisotuzumab adizutecan

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Also known as:

Temab-A ABT-700

Active trials that use this drug: 4

Cancer types include:

colon cancer non-small cell lung cancer rectal cancer small cell lung cancer

Tulmimetostat

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Also known as:

CPI-0209 DZR123

Active trials that use this drug: 4

Cancer types include:

mesothelioma ovarian cancer prostate cancer uterine cancer

Xaluritamig

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Also known as:

AMG 509

Active trials that use this drug: 4

Cancer types include:

prostate cancer

AMG 193

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Also known as:

AM-9747

Active trials that use this drug: 3

Cancer types include:

non-small cell lung cancer pancreas cancer small cell lung cancer

AMXT 1501 Dicaprate

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Also known as:

AMX 513 dicaprate

Active trials that use this drug: 3

Cancer types include:

brain tumor breast cancer melanoma sarcoma

AZD0901

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Also known as:

Sonesitatug vedotin CMG901

Active trials that use this drug: 3

Cancer types include:

pancreas cancer stomach cancer

AZD9574

No activity yet

Also known as:

palacaparib

Active trials that use this drug: 3

Cancer types include:

breast cancer ovarian cancer pancreas cancer prostate cancer uterine cancer

BGB-43395

No activity yet

Active trials that use this drug: 3

Cancer types include:

bladder cancer breast cancer non-small cell lung cancer ovarian cancer prostate cancer +3 more

BT8009

No activity yet

Also known as:

Zelenectide pevedotin BCY8245

Active trials that use this drug: 3

Cancer types include:

bladder cancer breast cancer non-small cell lung cancer small cell lung cancer

Cetrelimab

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Also known as:

JNJ-63723283

Active trials that use this drug: 3

Cancer types include:

non-small cell lung cancer prostate cancer small cell lung cancer

DB-1303/BNT323

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Also known as:

BNT-323

Active trials that use this drug: 3

Cancer types include:

breast cancer liver cancer non-small cell lung cancer small cell lung cancer stomach cancer +1 more

disitamab vedotin

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Also known as:

RC48 Aidixi

Active trials that use this drug: 3

Cancer types include:

bladder cancer breast cancer stomach cancer

Divarasib

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Also known as:

RG 6330

Active trials that use this drug: 3

Cancer types include:

colon cancer non-small cell lung cancer rectal cancer small cell lung cancer

Emavusertib

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Also known as:

CA-4948

Active trials that use this drug: 3

Cancer types include:

cervical cancer colon cancer esophageal cancer head and neck cancer pancreas cancer +2 more

Evorpacept

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Also known as:

ALX148

Active trials that use this drug: 3

Cancer types include:

breast cancer colon cancer ovarian cancer rectal cancer

GSK5764227

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Also known as:

HS-20093

Active trials that use this drug: 3

Cancer types include:

breast cancer cervical cancer colon cancer head and neck cancer kidney cancer +8 more

IMA203

Shows activity

Active trials that use this drug: 3

Cancer types include:

melanoma ovarian cancer sarcoma uterine cancer

Ipatasertib

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Also known as:

RG7440 GDC-0068

Active trials that use this drug: 3

Cancer types include:

breast cancer uterine cancer

JSB462

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Also known as:

Luxdegalutamide

Active trials that use this drug: 3

Cancer types include:

prostate cancer

LY3537982

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Also known as:

Olomorasib

Active trials that use this drug: 3

Cancer types include:

colon cancer non-small cell lung cancer ovarian cancer pancreas cancer rectal cancer +2 more

M7824

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Also known as:

Bintrafusp alfa

Active trials that use this drug: 3

Cancer types include:

bladder cancer kidney cancer prostate cancer sarcoma

MK-4830

Shows activity

Active trials that use this drug: 3

Cancer types include:

cervical cancer esophageal cancer head and neck cancer non-small cell lung cancer small cell lung cancer

Palazestrant

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Also known as:

OP-1250

Active trials that use this drug: 3

Cancer types include:

breast cancer

Peposertib

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Also known as:

M3814 MSC2490484A Nedisertib

Active trials that use this drug: 3

Cancer types include:

pancreas cancer prostate cancer sarcoma

Petosemtamab

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Also known as:

MCLA-158

Active trials that use this drug: 3

Cancer types include:

cervical cancer colon cancer esophageal cancer head and neck cancer rectal cancer +1 more

PF-07220060

Shows activity

Active trials that use this drug: 3

Cancer types include:

breast cancer non-small cell lung cancer prostate cancer small cell lung cancer uterine cancer

ProAgio

No activity yet

Also known as:

ACT-50

Active trials that use this drug: 3

Cancer types include:

breast cancer colon cancer pancreas cancer rectal cancer

REGN5678

Shows activity

Active trials that use this drug: 3

Cancer types include:

kidney cancer prostate cancer

RYZ101

Shows activity

Also known as:

225Ac-DOTATATE

Active trials that use this drug: 3

Cancer types include:

breast cancer pancreas cancer small cell lung cancer stomach cancer

Tiragolumab

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Also known as:

RO7092284 RG6058 MTIG7192A

Active trials that use this drug: 3

Cancer types include:

colon cancer liver cancer rectal cancer uterine cancer

TNG462

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Active trials that use this drug: 3

Cancer types include:

breast cancer gallbladder cancer kidney cancer liver cancer mesothelioma +4 more

Tuvusertib

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Also known as:

M1774 VXc-400 VRT-1363004 MSC2584415A +2 more

Active trials that use this drug: 3

Cancer types include:

colon cancer ovarian cancer rectal cancer uterine cancer

Ubamatamab

Shows activity

Also known as:

REGN4018

Active trials that use this drug: 3

Cancer types include:

ovarian cancer uterine cancer

Valemetostat

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Active trials that use this drug: 3

Cancer types include:

liver cancer prostate cancer small cell lung cancer

Zongertinib

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Also known as:

NSC-854531 BI-1810631

Active trials that use this drug: 3

Cancer types include:

breast cancer colon cancer esophageal cancer non-small cell lung cancer rectal cancer +2 more

[177Lu]Lu-NeoB

No activity yet

Also known as:

Lutetium-177 NeoBOMB1

Active trials that use this drug: 2

Cancer types include:

breast cancer

[68Ga]Ga-NeoB

No activity yet

Also known as:

NeoBOMB1

Active trials that use this drug: 2

Cancer types include:

breast cancer

ACR-368

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Also known as:

Prexasertib

Active trials that use this drug: 2

Cancer types include:

cervical cancer head and neck cancer uterine cancer

Alisertib

Shows activity

Also known as:

MLN8237

Active trials that use this drug: 2

Cancer types include:

breast cancer small cell lung cancer

AVZO-021

No activity yet

Also known as:

ARTS-021

Active trials that use this drug: 2

Cancer types include:

breast cancer ovarian cancer uterine cancer

AZD8205

Shows activity

Also known as:

puxitatug samrotecan

Active trials that use this drug: 2

Cancer types include:

breast cancer non-small cell lung cancer ovarian cancer small cell lung cancer uterine cancer

Azeliragon

No activity yet

Also known as:

TTP488 PF-04494700

Active trials that use this drug: 2

Cancer types include:

brain tumor pancreas cancer

Azenosertib

Shows activity

Also known as:

KP-2638

Active trials that use this drug: 2

Cancer types include:

ovarian cancer uterine cancer

BAY2927088

Shows activity

Active trials that use this drug: 2

Cancer types include:

bladder cancer breast cancer cervical cancer colon cancer esophageal cancer +10 more

Berzosertib

Shows activity

Also known as:

VX-970 VE-822 M6620

Active trials that use this drug: 2

Cancer types include:

small cell lung cancer

BI 764532

Shows activity

Also known as:

Obrixtamig

Active trials that use this drug: 2

Cancer types include:

non-small cell lung cancer small cell lung cancer

BMS-986340

No activity yet

Also known as:

anti-CCR8 imzokitug

Active trials that use this drug: 2

Cancer types include:

breast cancer cervical cancer colon cancer head and neck cancer kidney cancer +7 more

BNT324

Shows activity

Also known as:

DB-1311

Active trials that use this drug: 2

Cancer types include:

cervical cancer esophageal cancer head and neck cancer liver cancer melanoma +6 more

BTX-A51

Shows activity

Active trials that use this drug: 2

Cancer types include:

breast cancer sarcoma

Camizestrant

Shows activity

Also known as:

UNII-JUP57A8EPZ AZ 14066724 AZD9833

Active trials that use this drug: 2

Cancer types include:

breast cancer ovarian cancer

Carotuximab

No activity yet

Also known as:

C-SN6J DE-122 TRC-105

Active trials that use this drug: 2

Cancer types include:

non-small cell lung cancer prostate cancer small cell lung cancer

casdatifan

Shows activity

Also known as:

AB521

Active trials that use this drug: 2

Cancer types include:

kidney cancer

CBL0137

No activity yet

Also known as:

Curaxin 137

Active trials that use this drug: 2

Cancer types include:

brain tumor melanoma

CDX-1140

Shows activity

Also known as:

CDX 1140

Active trials that use this drug: 2

Cancer types include:

breast cancer ovarian cancer

CHS-114

Shows activity

Also known as:

SRF114

Active trials that use this drug: 2

Cancer types include:

cervical cancer colon cancer esophageal cancer head and neck cancer rectal cancer +1 more

Cirtuvivint

Shows activity

Also known as:

SM08502

Active trials that use this drug: 2

Cancer types include:

breast cancer ovarian cancer small cell lung cancer

CYAD-101

Shows activity

Active trials that use this drug: 2

Cancer types include:

colon cancer

Domvanalimab

Shows activity

Also known as:

GS-0154 AB-154

Active trials that use this drug: 2

Cancer types include:

cervical cancer head and neck cancer melanoma

EIK1001

Shows activity

Also known as:

BDB001

Active trials that use this drug: 2

Cancer types include:

melanoma non-small cell lung cancer small cell lung cancer

Ficerafusp alfa

Shows activity

Also known as:

BCA101 FMAB2

Active trials that use this drug: 2

Cancer types include:

cervical cancer colon cancer head and neck cancer ovarian cancer pancreas cancer +2 more

GDC-4198

Shows activity

Also known as:

RGT-419B RO7840734

Active trials that use this drug: 2

Cancer types include:

breast cancer

Gedatolisib

Shows activity

Also known as:

PKI-587 PF-05212384

Active trials that use this drug: 2

Cancer types include:

ovarian cancer prostate cancer uterine cancer

GEM/DOX + TGFBi expanded NK cells

No activity yet

Also known as:

TGF-beta imprinted NK cells

Active trials that use this drug: 2

Cancer types include:

breast cancer sarcoma

Iadademstat

Shows activity

Also known as:

ORY-1001 RG-6016 RO-7051790

Active trials that use this drug: 2

Cancer types include:

small cell lung cancer

iC9-CAR.B7-H3 T cells

No activity yet

Active trials that use this drug: 2

Cancer types include:

ovarian cancer pancreas cancer

iC9-GD2.CAR.IL-15 T-cells

No activity yet

Also known as:

GD2.CAR.15-Ts IC9-GD2-CD28-OX40

Active trials that use this drug: 2

Cancer types include:

brain tumor non-small cell lung cancer sarcoma small cell lung cancer

IMNN-001

Shows activity

Also known as:

GEN-1

Active trials that use this drug: 2

Cancer types include:

ovarian cancer

Investigational drugs